cAMP-induced desensitization of surface cAMP receptors in Dictyostelium: different second messengers mediate receptor phosphorylation, loss of ligand binding, degradation of receptor, and reduction of receptor mRNA levels.

Surface cAMP receptors on Dictyostelium cells are linked to several second messenger systems and mediate multiple physiological responses, including chemotaxis and differentiation. Activation of the receptor also triggers events which desensitize signal transduction. These events include the followi...

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Dettagli Bibliografici
Pubblicato in:Mol Biol Cell
Autori principali: Van Haastert, P J, Wang, M, Bominaar, A A, Devreotes, P N, Schaap, P
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Cell Biology 1992
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275616/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1323348/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.3.6.603
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