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An Essential Set of Basic DNA Response Elements Is Required for Receptor-Dependent Transcription of the Lecithin:Retinol Acyltransferase (Lrat) Gene

Lecithin:retinol acyltransferase (LRAT) is essential for vitamin A storage. Nuclear run-on assays demonstrated transcriptional regulation of the Lrat gene in vivo by all-trans-retinoic acid (RA) and other retinoids. Analysis of a 2.5 kb segment of rat genomic DNA revealed that the region ~300 bp ups...

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Détails bibliographiques
Auteurs principaux: Zolfaghari, Reza, Ross, A. Catharine
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756149/
https://ncbi.nlm.nih.gov/pubmed/19665987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2009.08.001
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