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Activation of human cyclin-dependent kinases in vitro.

We have analyzed the activation of human cyclin-dependent kinases in a cell-free system. Human CDC2, cyclin-dependent kinase 2 (CDK2), cyclin A, and cyclin B1 were produced in insect cells by infection with recombinant baculoviruses. CDC2 or CDK2 monomers in lysates of infected cells could be activa...

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Bibliographic Details
Published in:Mol Biol Cell
Main Authors: Desai, D, Gu, Y, Morgan, D O
Format: Artigo
Language:Inglês
Published: American Society for Cell Biology 1992
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275609/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1535244/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.3.5.571
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