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Human Manganese Superoxide Dismutase Tyrosine 34 Contribution to Structure and Catalysis

Superoxide dismutase (SOD) enzymes are critical in controlling levels of reactive oxygen species (ROS) that are linked to aging, cancer and neurodegenerative disease. Superoxide (O(2) (•−)) produced during respiration is removed by the product of the SOD2 gene, the homotetrameric manganese superoxid...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Perry, J. Jefferson P., Hearn, Amy S., Cabelli, Diane E., Nick, Harry S., Tainer, John A., Silverman, David N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756076/
https://ncbi.nlm.nih.gov/pubmed/19265433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi8023288
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