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Human Manganese Superoxide Dismutase Tyrosine 34 Contribution to Structure and Catalysis

Superoxide dismutase (SOD) enzymes are critical in controlling levels of reactive oxygen species (ROS) that are linked to aging, cancer and neurodegenerative disease. Superoxide (O(2) (•−)) produced during respiration is removed by the product of the SOD2 gene, the homotetrameric manganese superoxid...

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Detalhes bibliográficos
Main Authors: Perry, J. Jefferson P., Hearn, Amy S., Cabelli, Diane E., Nick, Harry S., Tainer, John A., Silverman, David N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756076/
https://ncbi.nlm.nih.gov/pubmed/19265433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi8023288
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