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gadem: A Genetic Algorithm Guided Formation of Spaced Dyads Coupled with an EM Algorithm for Motif Discovery
Genome-wide analyses of protein binding sites generate large amounts of data; a ChIP dataset might contain 10,000 sites. Unbiased motif discovery in such datasets is not generally feasible using current methods that employ probabilistic models. We propose an efficient method, gadem, which combines s...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc.
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2756050/ https://ncbi.nlm.nih.gov/pubmed/19193149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2008.16TT |
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