Estradiol promotes proliferation of dopaminergic precursors resulting in a higher proportion of dopamine neurons derived from mouse embryonic stem cells

Estradiol protects dopamine neurons of the substantia nigra from toxic insults. Such neurons succumb in Parkinson’s disease; one strategy for restoring dopamine deficiency is cell therapy with neurons differentiated from embryonic stem cells. We investigated the effects of 17β-estradiol on dopaminer...

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Bibliographic Details
Main Authors: Díaz, Néstor F., Díaz-Martínez, Néstor E., Camacho-Arroyo, Ignacio, Velasco, Iván
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756038/
https://ncbi.nlm.nih.gov/pubmed/19379802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijdevneu.2009.04.002
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