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Estradiol promotes proliferation of dopaminergic precursors resulting in a higher proportion of dopamine neurons derived from mouse embryonic stem cells
Estradiol protects dopamine neurons of the substantia nigra from toxic insults. Such neurons succumb in Parkinson’s disease; one strategy for restoring dopamine deficiency is cell therapy with neurons differentiated from embryonic stem cells. We investigated the effects of 17β-estradiol on dopaminer...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2756038/ https://ncbi.nlm.nih.gov/pubmed/19379802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijdevneu.2009.04.002 |
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