Endogenous Elevation of Homocysteine Induces Retinal Neuron Death in the Cystathionine-β-Synthase Mutant Mouse

PURPOSE: To determine the effects of endogenous elevation of homocysteine on the retina using the cystathionine β-synthase (cbs) mutant mouse. METHODS: Retinal homocysteine in cbs mutant mice was measured by high-performance liquid chromatography (HPLC). Retinal cryosections from cbs(−/−) mice and c...

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Autori principali: Ganapathy, Preethi S., Moister, Brent, Roon, Penny, Mysona, Barbara A., Duplantier, Jennifer, Dun, Ying, Moister, Tracy K. V. E., Farley, Marlena J., Prasad, Puttur D., Liu, Kebin, Smith, Sylvia B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756015/
https://ncbi.nlm.nih.gov/pubmed/19357353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-3402
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