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Relative Contributions of Cystathionine β-Synthase and γ-Cystathionase to H(2)S Biogenesis via Alternative Trans-sulfuration Reactions

In mammals, the two enzymes in the trans-sulfuration pathway, cystathionine β-synthase (CBS) and cystathionine γ-lyase (CSE), are believed to be chiefly responsible for hydrogen sulfide (H(2)S) biogenesis. In this study, we report a detailed kinetic analysis of the human and yeast CBS-catalyzed reac...

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Bibliografiske detaljer
Main Authors: Singh, Sangita, Padovani, Dominique, Leslie, Rachel A., Chiku, Taurai, Banerjee, Ruma
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755967/
https://ncbi.nlm.nih.gov/pubmed/19531479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.010868
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