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Alternative pathways for the sorting of soluble vacuolar proteins in yeast: a vps35 null mutant missorts and secretes only a subset of vacuolar hydrolases.

vps35 mutants of Saccharomyces cerevisiae exhibit severe defects in the localization of carboxypeptidase Y, a soluble vacuolar hydrolase. We have cloned the wild-type VPS35 gene by complementation of the vacuolar protein sorting defect exhibited by the vps35-17 mutant. Sequence analysis revealed an...

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Argitaratua izan da:Mol Biol Cell
Egile Nagusiak: Paravicini, G, Horazdovsky, B F, Emr, S D
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Cell Biology 1992
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275592/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1498362/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.3.4.415
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