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Molecular Mimicry in Innate Immunity: CRYSTAL STRUCTURE OF A BACTERIAL TIR DOMAIN

Macrophages detect pathogen infection via the activation of their plasma membrane-bound Toll-like receptor proteins (TLRs). The heterotypic interaction between the Toll/interleukin-1 receptor (TIR) domains of TLRs and adaptor proteins, like Myeloid differentiation primary response gene 88 (MyD88), i...

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Detalhes bibliográficos
Main Authors: Chan, Siew Leong, Low, Lieh Yoon, Hsu, Simon, Li, Sheng, Liu, Tong, Santelli, Eugenio, Le Negrate, Gaelle, Reed, John C., Woods, Virgil L., Pascual, Jaime
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755863/
https://ncbi.nlm.nih.gov/pubmed/19535337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C109.007591
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