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Helix Straightening as an Activation Mechanism in the Gelsolin Superfamily of Actin Regulatory Proteins
Villin and gelsolin consist of six homologous domains of the gelsolin/cofilin fold (V1–V6 and G1–G6, respectively). Villin differs from gelsolin in possessing at its C terminus an unrelated seventh domain, the villin headpiece. Here, we present the crystal structure of villin domain V6 in an environ...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2755850/ https://ncbi.nlm.nih.gov/pubmed/19491107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.019760 |
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