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X-linked Inhibitor of Apoptosis Protein and Its E3 Ligase Activity Promote Transforming Growth Factor-β-mediated Nuclear Factor-κB Activation during Breast Cancer Progression
The precise sequence of events that enable mammary tumorigenesis to convert transforming growth factor-β (TGF-β) from a tumor suppressor to a tumor promoter remains incompletely understood. We show here that X-linked inhibitor of apoptosis protein (xIAP) is essential for the ability of TGF-β to stim...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Biochemistry and Molecular Biology
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2755844/ https://ncbi.nlm.nih.gov/pubmed/19531477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.018374 |
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