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Molecular flip–flops formed by overlapping Fis sites

The DNA-binding protein Fis frequently uses pairs of sites 7 or 11 base pairs (bp) apart. Two overlapping Fis sites separated by 11 bp are found in the Escherichia coli origin of chromosomal replication. Only one of these sites is bound by Fis at a time, so the structure is a molecular flip–flop tha...

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Bibliografiske detaljer
Main Authors: Hengen, Paul N., Lyakhov, Ilya G., Stewart, Lisa E., Schneider, Thomas D.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC275571/
https://ncbi.nlm.nih.gov/pubmed/14602927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg877
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