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Solution Structure of Human Cardiac Troponin C in Complex with the Green Tea Polyphenol, (−)-Epigallocatechin 3-Gallate

Heart muscle contraction is regulated by Ca(2+) binding to the thin filament protein troponin C. In cardiovascular disease, the myofilament response to Ca(2+) is often altered. Compounds that rectify this perturbation are of considerable interest as therapeutics. Plant flavonoids have been found to...

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Autori principali: Robertson, Ian M., Li, Monica X., Sykes, Brian D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755708/
https://ncbi.nlm.nih.gov/pubmed/19542563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.021352
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