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In vitro and in vivo modulations of benzo[c]phenanthrene–DNA adducts by DNA mismatch repair system

Benzo[c]phenanthrene dihydrodiol epoxide (B[c] PhDE) is well known as an important environmental chemical carcinogen that preferentially modifies DNA in adenine residues. However, the molecular mechanism by which B[c]PhDE induces tumorigenesis is not fully understood. In this report, we demonstrate...

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Hlavní autoři: Wu, Jianxin, Zhu, Bei-Bei, Yu, Jin, Zhu, Hong, Qiu, Lu, Kindy, Mark S., Gu, Liya, Seidel, Albrecht, Li, Guo-Min
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC275569/
https://ncbi.nlm.nih.gov/pubmed/14602900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg875
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