Загрузка...
Coupling Sequence-specific Recognition to DNA Modification
Enzymes that modify DNA are faced with significant challenges in specificity for both substrate binding and catalysis. We describe how single hydrogen bonds between M.HhaI, a DNA cytosine methyltransferase, and its DNA substrate regulate the positioning of a peptide loop which is ∼28 Å away. Stopped...
Сохранить в:
| Главные авторы: | , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2009
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2755677/ https://ncbi.nlm.nih.gov/pubmed/19497854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.015966 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|