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DNA damage induces transcriptional activation of p73 by removing C-EBPα repression on E2F1
p73 is a member of the p53 family often overexpressed in human cancer. Its regulation, particularly following DNA damage, is different from that of p53. Following DNA damage, we found induction of p73 at both the protein and mRNA levels. Furthermore, by using different p73 promoter fragments, we fou...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC275563/ https://ncbi.nlm.nih.gov/pubmed/14602923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg869 |
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