Nitrite therapy after cardiac arrest reduces ROS generation, improves cardiac and neurological function and enhances survival via reversible inhibition of mitochondrial complex I

BACKGROUND: Three-fourths of cardiac arrest survivors die prior to hospital discharge or suffer significant neurological injury. Excepting therapeutic hypothermia and revascularization, no novel therapies have been developed that improve survival or cardiac and neurological function after resuscitat...

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Main Authors: Dezfulian, Cameron, Shiva, Sruti, Alekseyenko, Aleksey, Pendyal, Akshay, Beiser, DG, Munasinghe, Jeeva P., Anderson, Stasia A., Chesley, Christopher F., Hoek, TL Vanden, Gladwin, Mark T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755623/
https://ncbi.nlm.nih.gov/pubmed/19704094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.109.853267
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