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Gene essentiality determines chromosome organisation in bacteria

In Escherichia coli and Bacillus subtilis, essentiality, not expressivity, drives the distribution of genes between the two replicating strands. Although essential genes tend to be coded in the leading replicating strand, the underlying selective constraints and the evolutionary extent of these find...

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Détails bibliographiques
Auteurs principaux: Rocha, Eduardo P. C., Danchin, Antoine
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC275555/
https://ncbi.nlm.nih.gov/pubmed/14602916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg859
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