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Leucine Leucine-37 Uses Formyl Peptide Receptor–Like 1 to Activate Signal Transduction Pathways, Stimulate Oncogenic Gene Expression, and Enhance the Invasiveness of Ovarian Cancer Cells

Emerging evidence suggests that the antimicrobial peptide, leucine leucine-37 (LL-37), could play a role in the progression of solid tumors. LL-37 is expressed as the COOH terminus of human cationic antimicrobial protein-18 (hCAP-18) in ovarian, breast, and lung cancers. Previous studies have shown...

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Detalhes bibliográficos
Main Authors: Coffelt, Seth B., Tomchuck, Suzanne L., Zwezdaryk, Kevin J., Danka, Elizabeth S., Scandurro, Aline B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755540/
https://ncbi.nlm.nih.gov/pubmed/19491199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-08-0326
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