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A fast and efficient gene-network reconstruction method from multiple over-expression experiments

BACKGROUND: Reverse engineering of gene regulatory networks presents one of the big challenges in systems biology. Gene regulatory networks are usually inferred from a set of single-gene over-expressions and/or knockout experiments. Functional relationships between genes are retrieved either from th...

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Detalhes bibliográficos
Main Authors: Stokić, Dejan, Hanel, Rudolf, Thurner, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755483/
https://ncbi.nlm.nih.gov/pubmed/19686586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-253
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