Transgenic Mice Lacking Serotonin Neurons Have Severe Apnea and High Mortality during Development

Central serotonin (5-HT) neurons modulate many vital brain functions, including respiratory control. Whether breathing depends critically on 5-HT neurons, or whether their influence is excitatory or inhibitory, remains controversial. Here we show that neonatal Lmx1b(flox/flox;ePet-Cre/+) mice (also...

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Detalhes bibliográficos
Main Authors: Hodges, Matthew R., Wehner, Mackenzie, Aungst, Jason, Smith, Jeffrey C., Richerson, George B.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755228/
https://ncbi.nlm.nih.gov/pubmed/19692608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1963-09.2009
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