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Highly Efficient Detection of Single Fluorophores in Blood Serum Samples with High Autofluorescence

Single molecule detection (SMD) is usually performed on surface-immobilized molecules with diffraction-limited observation volumes, typically with confocal optics to suppress background from the sample and instrument. In this paper we consider the more difficult task of detecting single fluorophores...

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Autori principali: Fu, Yi, Zhang, Jian, Lakowicz, Joseph R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755222/
https://ncbi.nlm.nih.gov/pubmed/19192209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1751-1097.2008.00500.x
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