Hsp72 Induces Inflammation and Regulates Cytokine Production in Airway Epithelium through a TLR4- and NF-κB-Dependent Mechanism

Heat shock proteins are generally regarded as intracellular proteins acting as molecular chaperones; however, Hsp72 is also detected in the extracellular compartment. Hsp72 has been identified in the bronchoalveolar lavage fluid (BALF) of patients with acute lung injury. To address whether Hsp72 dir...

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Autores principales: Chase, Margaret A., Wheeler, Derek S., Lierl, Kristin M., Hughes, Valerie S., Wong, Hector R., Page, Kristen
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755189/
https://ncbi.nlm.nih.gov/pubmed/17947709
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