Imaging of Peripheral Benzodiazepine Receptor Expression as Biomarkers of Detrimental versus Beneficial Glial Responses in Mouse Models of Alzheimer's and Other CNS Pathologies

We demonstrate the significance of peripheral benzodiazepine receptor (PBR) imaging in living mouse models of Alzheimer's disease (AD) as biomarkers and functional signatures of glial activation. By radiochemically and immunohistochemically analyzing murine models of the two pathological hallma...

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Main Authors: Ji, Bin, Maeda, Jun, Sawada, Makoto, Ono, Maiko, Okauchi, Takashi, Inaji, Motoki, Zhang, Ming-Rong, Suzuki, Kazutoshi, Ando, Kiyoshi, Staufenbiel, Matthias, Trojanowski, John Q., Lee, Virginia M. Y., Higuchi, Makoto, Suhara, Tetsuya
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2008
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755188/
https://ncbi.nlm.nih.gov/pubmed/19020019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2312-08.2008
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