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Role of phosphorylation in p34cdc2 activation: identification of an activating kinase.

Phosphorylation of p34cdc2 can both positively and negatively regulate its kinase activity. We have mapped two phosphorylation sites in Xenopus p34cdc2 to Thr-14 and Tyr-15 within the putative ATP-binding region of p34cdc2. Mutation of these sites to Ala-14 and Phe-15 has no effect on the final hist...

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Autores principales: Solomon, M J, Lee, T, Kirschner, M W
Formato: Artigo
Lenguaje:Inglês
Publicado: 1992
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC275499/
https://ncbi.nlm.nih.gov/pubmed/1532335
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