Chronic myeloid leukemia patients with the e13a2 BCR-ABL fusion transcript have inferior responses to imatinib compared to patients with the e14a2 transcript

BACKGROUND: Chronic myeloid leukemia is characterized by a reciprocal translocation between chromosomes 9 and 22, creating the fusion gene BCR-ABL. The clinical significance of the type of BCR-ABL transcript in newly diagnosed patients in chronic phase treated with imatinib 400 mg from initial diagn...

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Detalhes bibliográficos
Main Authors: Lucas, Claire M., Harris, Robert J., Giannoudis, Athina, Davies, Andrea, Knight, Katy, Watmough, Sarah J., Wang, Lihui, Clark, Richard E.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754951/
https://ncbi.nlm.nih.gov/pubmed/19713230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.009134
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