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1α,25(OH)(2)D(3) is an Autocrine Regulator of Extracellular Matrix Turnover and Growth Factor Release via ERp60 Activated Matrix Vesicle Metalloproteinases
Growth plate chondrocytes produce proteoglycan-rich type II collagen extracellular matrix (ECM). During cell maturation and hypertrophy, ECM is reorganized via a process regulated by 1α,25(OH)(2)D(3) and involving matrix metalloproteinases (MMPs), including MMP-3and MMP-2. 1α,25(OH)(2)D(3) regulates...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2754708/ https://ncbi.nlm.nih.gov/pubmed/17224270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2006.11.003 |
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