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Energetics of echinomycin binding to DNA

Differential scanning calorimetry and UV thermal denaturation have been used to determine a complete thermodynamic profile for the bis-intercalative interaction of the peptide antibiotic echinomycin with DNA. The new calorimetric data are consistent with all previously published binding data, and af...

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Detalles Bibliográficos
Main Authors: Leng, Fenfei, Chaires, Jonathan B., Waring, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC275468/
https://ncbi.nlm.nih.gov/pubmed/14576305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg826
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