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Engineering insulin-like growth factor-1 for local delivery

Insulin-like growth factor-1 (IGF-1) is a small protein that promotes cell survival and growth, often acting over long distances. Although for decades IGF-1 has been considered to have therapeutic potential, systemic side effects of IGF-1 are significant, and local delivery of IGF-1 for tissue repai...

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Autors principals: Tokunou, Tomotake, Miller, Rachel, Patwari, Parth, Davis, Michael E., Segers, Vincent F. M., Grodzinsky, Alan J., Lee, Richard T.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754573/
https://ncbi.nlm.nih.gov/pubmed/18285400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.07-100925
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