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The Replicase Gene of Avian Coronavirus Infectious Bronchitis Virus Is a Determinant of Pathogenicity

We have previously demonstrated that the replacement of the S gene from an avirulent strain (Beaudette) of infectious bronchitis virus (IBV) with an S gene from a virulent strain (M41) resulted in a recombinant virus (BeauR-M41(S)) with the in vitro cell tropism of the virulent virus but that was st...

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Detalhes bibliográficos
Main Authors: Armesto, Maria, Cavanagh, Dave, Britton, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754531/
https://ncbi.nlm.nih.gov/pubmed/19816578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007384
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