Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4(+) hemangiocytes

The mechanisms through which hematopoietic cytokines accelerate revascularization are unknown. Here, we show that the magnitude of cytokine-mediated release of SDF-1 from platelets and the recruitment of nonendothelial CXCR4(+)VEGFR1(+) hematopoietic progenitors, ‘hemangiocytes,’ constitute the majo...

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Autori principali: Jin, David K, Shido, Koji, Kopp, Hans-Georg, Petit, Isabelle, Shmelkov, Sergey V, Young, Lauren M, Hooper, Andrea T, Amano, Hideki, Avecilla, Scott T, Heissig, Beate, Hattori, Koichi, Zhang, Fan, Hicklin, Daniel J, Wu, Yan, Zhu, Zhenping, Dunn, Ashley, Salari, Hassan, Werb, Zena, Hackett, Neil R, Crystal, Ronald G, Lyden, David, Rafii, Shahin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754288/
https://ncbi.nlm.nih.gov/pubmed/16648859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1400
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