Sister Chromatids Fail to Separate during an Induced Endoreplication Cycle in Drosophila Embryos

When mitosis is bypassed, as in some cancer cells or in natural endocycles, sister chromosomes remain paired and produce four-stranded diplochromosomes or polytene chromosomes. Cyclin/Cdk1 inactivation blocks entry into mitosis and can reset G2 cells to G1, allowing another round of replication [1]....

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Main Authors: Vidwans, Smruti J., DiGregorio, Paul J., Shermoen, Antony W., Foat, Barrett, Iwasa, Janet, Yakubovich, Nikita, O'Farrell, Patrick H.
Format: Artigo
Jezik:Inglês
Izdano: 2002
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754250/
https://ncbi.nlm.nih.gov/pubmed/12015119
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