Contribution of Chymase-Dependent Angiotensin II Formation to the Progression of Tubulointerstitial Fibrosis in Obstructed Kidneys in Hamsters

Recent studies indicate a role of chymase in the regulation of angiotensin II (AngII) formation in cardiovascular and renal tissues. We investigated a possible contribution of chymase to AngII formation and to renal fibrosis in unilateral ureteral obstruction (UUO). Eight-week-old Syrian hamsters we...

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Autores principales: Fan, Yu-Yan, Nishiyama, Akira, Fujisawa, Yoshihide, Kobori, Hiroyuki, Nakano, Daisuke, Matsuura, Junji, Hase, Naoki, Hitomi, Hirofumi, Kiyomoto, Hideyasu, Urata, Hidenori, Kohno, Masakazu
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754182/
https://ncbi.nlm.nih.gov/pubmed/19721329
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