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TFIIIB is phosphorylated, disrupted and selectively released from tRNA promoters during mitosis in vivo

Mitosis involves a generalized repression of gene expression. In the case of RNA polymerase III transcription, this is due to phosphorylation-mediated inactivation of TFIIIB, an essential complex comprising the TATA-binding protein TBP and the TAF subunits Brf1 and Bdp1. In HeLa cells, this repressi...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Fairley, Jennifer A., Scott, Pamela H., White, Robert J.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275401/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14592981/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg544
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