Expression of interferon-γ and tumour necrosis factor-α messenger RNA does not correlate with protection in guinea pigs challenged with virulent Mycobacterium tuberculosis by the respiratory route

Cytokine messenger RNA (mRNA) expression was investigated in the spleen and lung digest cells of bacillus Calmette–Guérin (BCG)-vaccinated and non-vaccinated guinea pigs following low-dose, pulmonary exposure to virulent Mycobacterium tuberculosis. After purified protein derivative (PPD) stimulation...

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Библиографические подробности
Главные авторы: Jeevan, Amminikutty, Bonilla, Diana Lucia, McMurray, David Neil
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Science Inc 2009
Предметы:
Original Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753903/
https://ncbi.nlm.nih.gov/pubmed/19016908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.02962.x
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