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Developmentally programmed endoreduplication in animals

Development of a fertilized egg into an adult human requires trillions of cell divisions, the vast majority of which duplicate their genome once and only once. Nevertheless, trophoblast giant cells and megakaryocytes in mammals circumvent this rule by duplicating their genome multiple times without...

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Main Authors: Ullah, Zakir, Lee, Chrissie Y., Lilly, Mary A., DePamphilis, Melvin L.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753833/
https://ncbi.nlm.nih.gov/pubmed/19372757
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