Estrogen treatment decreases matrix metalloproteinase (MMP)-9 in autoimmune demyelinating disease through estrogen receptor alpha (ERα)

Matrix metalloproteinases (MMPs) play a crucial role in migration of inflammatory cells into the central nervous system (CNS). Levels of MMP-9 are elevated in multiple sclerosis (MS) and predict the occurrence of new active lesions on magnetic resonance imaging (MRI). This translational study aims t...

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Bibliographische Detailangaben
Hauptverfasser: Gold, Stefan M, Sasidhar, Manda V, Morales, Laurie B, Du, Sienmi, Sicotte, Nancy L, Tiwari-Woodruff, Seema K., Voskuhl, Rhonda R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753699/
https://ncbi.nlm.nih.gov/pubmed/19668239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2009.79
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