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Structural basis of HIV-1 activation by NF-kappaB - a higher-order complex of p50:RelA bound to the HIV-1 LTR

The activation and latency of human immunodeficiency virus-1 (HIV-1) is tightly controlled by the transcriptional activity of its long terminal repeat region (LTR). The LTR is regulated by viral proteins as well as host factors, including the nuclear factor kappaB (NF-kappaB) that becomes activated...

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Библиографические подробности
Главные авторы: Stroud, James C, Oltman, Amy, Han, Aidong, Bates, Darren L., Chen, Lin
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753696/
https://ncbi.nlm.nih.gov/pubmed/19683540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.08.023
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