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The Amidase Domain of Lipoamidase Specifically Inactivates Lipoylated Proteins In Vivo

BACKGROUND: In the 1950s, Reed and coworkers discovered an enzyme activity in Streptococcus faecalis (Enterococcus faecalis) extracts that inactivated the Escherichia. coli and E. faecalis pyruvate dehydrogenase complexes through cleavage of the lipoamide bond. The enzyme that caused this lipoamidas...

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Bibliographic Details
Main Authors: Spalding, Maroya D., Prigge, Sean T.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753649/
https://ncbi.nlm.nih.gov/pubmed/19812687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007392
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