Mitochondrial DNA Mutation Stimulates Prostate Cancer Growth in Bone Stromal Environment

BACKGROUND AND OBJECTIVES: Mitochondrial DNA (mtDNA) mutations, inherited and somatically acquired, are common in clinical prostate cancer. We have developed model systems designed to study specific mtDNA mutations in controlled experiments. Because prostate cancer frequently metastasizes to bone we...

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Detalhes bibliográficos
Main Authors: Arnold, Rebecca S., Sun, Carrie Q., Richards, Jendai C., Grigoriev, Galina, Coleman, Ilsa M., Nelson, Peter S., Hsieh, Chia-Ling, Lee, Jae K., Xu, Zhiheng, Rogatko, Andre, Osunkoya, Adeboye O., Zayzafoon, Majd, Chung, Leland, Petros, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753601/
https://ncbi.nlm.nih.gov/pubmed/18850577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.20854
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