Beta4 integrin promotes osteosarcoma metastasis and interacts with ezrin

The development of pulmonary metastasis is the major cause of death in osteosarcoma, and its molecular basis is poorly understood. In this study, we show that β4 integrin is highly expressed in human osteosarcoma cell lines and tumor samples. Furthermore, highly metastatic MNNG-HOS cells have increa...

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Bibliografski detalji
Glavni autori: Wan, Xiaolin, Kim, Su Young, Guenther, Lillian M, Mendoza, Arnulfo, Briggs, Joseph, Yeung, Choh, Currier, Duane, Zhang, Hua, Mackall, Crystal, Li, Wan-Ju, Tuan, Rocky S, Deyrup, Andrea T, Khanna, Chand, Helman, Lee
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753583/
https://ncbi.nlm.nih.gov/pubmed/19597468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.206
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