Beta4 integrin promotes osteosarcoma metastasis and interacts with ezrin

The development of pulmonary metastasis is the major cause of death in osteosarcoma, and its molecular basis is poorly understood. In this study, we show that β4 integrin is highly expressed in human osteosarcoma cell lines and tumor samples. Furthermore, highly metastatic MNNG-HOS cells have increa...

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Detalhes bibliográficos
Main Authors: Wan, Xiaolin, Kim, Su Young, Guenther, Lillian M, Mendoza, Arnulfo, Briggs, Joseph, Yeung, Choh, Currier, Duane, Zhang, Hua, Mackall, Crystal, Li, Wan-Ju, Tuan, Rocky S, Deyrup, Andrea T, Khanna, Chand, Helman, Lee
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753583/
https://ncbi.nlm.nih.gov/pubmed/19597468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.206
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