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The impact of population size on the evolution of asexual microbes on smooth versus rugged fitness landscapes

BACKGROUND: It is commonly thought that large asexual populations evolve more rapidly than smaller ones, due to their increased rate of beneficial mutations. Less clear is how population size influences the level of fitness an asexual population can attain. Here, we simulate the evolution of bacteri...

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Detalles Bibliográficos
Main Authors: Handel, Andreas, Rozen, Daniel E
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753573/
https://ncbi.nlm.nih.gov/pubmed/19765292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-9-236
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