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SPINAL ANTINOCICEPTIVE ACTION OF LOPERAMIDE IS MEDIATED BY OPIOID RECEPTORS IN THE FORMALIN TEST IN RATS

Opioids like morphine produce antinociception after intrathecal administration. Being hydrophilic in nature, morphine also spreads rostrally and produces respiratory depression. Loperamide has been reported to produced antinociception after both intracisternal and intrathecal administration. It is a...

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Main Authors: RAY, SUBRATA BASU, YAKSH, TONY L
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753543/
https://ncbi.nlm.nih.gov/pubmed/18973791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2008.10.067
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