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Induction of MMP-1 (Collagenase-1) by Relaxin in fibrocartilaginous cells requires both the AP-1 and PEA-3 promoter sites
OBJECTIVES: Relaxin induces the matrix metalloproteinase MMP-1 (collagenase-1) in TMJ fibrocartilaginous cells, and this response is potentiated by β-estradiol. We identified the MMP-1 promoter sites and transcription factors that are induced by relaxin with or without β-estradiol in fibrocartilagin...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2753518/ https://ncbi.nlm.nih.gov/pubmed/19627519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1601-6343.2009.01451.x |
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