Psychotropic drugs up-regulate the expression of cholesterol transport proteins including ApoE in cultured human CNS- and liver cells

BACKGROUND: Disturbances in lipid homeostasis and myelination have been proposed in the pathophysiology of schizophrenia and bipolar disorder. We have previously shown that several antipsychotic and antidepressant drugs increase lipid biosynthesis through activation of the Sterol Regulatory Element-...

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Hlavní autoři: Vik-Mo, Audun O, Fernø, Johan, Skrede, Silje, Steen, Vidar M
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753324/
https://ncbi.nlm.nih.gov/pubmed/19715613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-9-10
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