Cytoplasmic Relaxation of Active Eph Controls Ephrin Shedding by ADAM10

Release of cell surface-bound ligands by A-Disintegrin-And-Metalloprotease (ADAM) transmembrane metalloproteases is essential for signalling by cytokine, cell adhesion, and tyrosine kinase receptors. For Eph receptor ligands, it provides the switch between cell-cell adhesion and repulsion. Ligand sh...

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Détails bibliographiques
Auteurs principaux: Janes, Peter W., Wimmer-Kleikamp, Sabine H., Frangakis, Achilleas S., Treble, Kane, Griesshaber, Bettina, Sabet, Ola, Grabenbauer, Markus, Ting, Alice Y., Saftig, Paul, Bastiaens, Philippe I., Lackmann, Martin
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2009
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753297/
https://ncbi.nlm.nih.gov/pubmed/19823572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000215
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