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Imaging Specific Cell Surface Protease Activity in Living Cells Using Reengineered Bacterial Cytotoxins

The scarcity of methods to visualize the activity of individual cell surface proteases in situ has hampered basic research and drug development efforts. In this chapter, we describe a simple, sensitive, and noninvasive assay that uses nontoxic reengineered bacterial cytotoxins with altered protease...

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Hlavní autoři: Hobson, John P., Liu, Shihui, Leppla, Stephen H., Bugge, Thomas H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753202/
https://ncbi.nlm.nih.gov/pubmed/19377967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-60327-003-8_7
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