Impaired dense core vesicle maturation in Caenorhabditis elegans mutants lacking Rab2

Despite a key role for dense core vesicles (DCVs) in neuronal function, there are major gaps in our understanding of DCV biogenesis. A genetic screen for Caenorhabditis elegans mutants with behavioral defects consistent with impaired DCV function yielded five mutations in UNC-108 (Rab2). A genetic a...

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Detalhes bibliográficos
Main Authors: Edwards, Stacey L., Charlie, Nicole K., Richmond, Janet E., Hegermann, Jan, Eimer, Stefan, Miller, Kenneth G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753164/
https://ncbi.nlm.nih.gov/pubmed/19797080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200902095
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