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The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice
The dynamin-related guanosine triphosphatase Drp1 mediates the division of mitochondria and peroxisomes. To understand the in vivo function of Drp1, complete and tissue-specific mouse knockouts of Drp1 were generated. Drp1-null mice die by embryonic day 11.5. This embryonic lethality is not likely c...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2753156/ https://ncbi.nlm.nih.gov/pubmed/19752021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200903065 |
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